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In 2008 the International Headache Society (IHS) published guidelines on “evaluation and registration of adverse events in clinical drug trials in migraine (Cephalalgia 2008; 28: 683-688). In this study we evaluated whether these guidelines on adverse events (AEs) subsequently were adhered to by reviewing , randomized, controlled trials (RCTs) on migraine drug treatment published in the three leading headache journals for the last 4 years.

EHMTI-0120. Are the IHS’ recommendations for evaluation and registration of adverse events in drug trials in migraine being followed ?