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Background A synergic association between acetylsalycilic acid, acetaminophen, caffeine in doses 3-4 times lower than similar combinations and chlorpheniramine was patented and marketed as analgesic drug. A previous study proved the non-inferiority of a unique dose of treatment using Algopirin, versus Excedrin similar association. Aim of the research was to prove superiority of two tablets Algopirin versus one tablet Excedrin in treating migraine.

EHMTI-0126. Superiority of algopirin® versus excedrin® in treating migraine. Individual pain values and pain curves comparisons