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Method Adult patients with CM attending the Hull migraine clinic were offered Botox based on clinical needs using the PREEMPT protocol. Headache diaries were maintained for at least 30 days prior to and continuously after Botox (July 2010 and January 2014). Data were extracted for headache, migraine, and headache-free days. A responder was defined as one with either a 50% reduction in either headache days or migraine days an increment in crystal clear days twice that of the baseline.

the journal of headache and pain

EHMTI-0102. Prospective analysis of the use of onabotulinumtoxina (botox®) In the treatment of chronic migraine; real-life data in 299 patients from hull, UK