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Aims The objectives of the present study were to determine the prevalence of anxiety and depression in migraine patients and to assess the relation of frequency, severity and impact of headaches with depression and anxiety. Methods In this cross-sectional study we included migraine patients based on ICHD-2 criteria from four clinics in Isfahan, Iran. HADS, HIT-6 and a symptom questionnaire were fulfilled by the patients. Each patient was asked to determine number of headache days per month (HDPM) and also headache severity by numeric rating scale (NRS). NRS is defined as a scale for severity of pain from zero to 10 that is described by the patient (zero stands for lack of pain and 10 describes the worst pain ever experienced by the patient). Regards to odd questions summation of HADS scores’ we determined depression score (patients with sores more than 7 were assumed as depressed) and we calculated anxiety score by summing the even questions of HADS scores (patients with sores more than 7 were assumed as anxious). The student T test was used to compare the mean scores between two groups. Results In this study 126 migraine patients with mean (±SD) age of 32.44 ± 9.94 and 65.1% female gender were included. Of the participants, 100 (79.4%) and 56 (44.4%) had anxiety and depression according to the HADS questionnaire respectively. Patients with depression got significantly higher NRS and HDPM scores (P = 0.004 and 0.031 resp.) than those without depression. But HIT-6 total score was not different statistically between them (P = 0.125). There were no significant differences between patients with and without anxiety for total HIT-6, NRS and HDPM scores (P = 0.275, 0.635 and 0.057 resp.). Conclusions

EHMTI-0057. Anxiety and depression in migraine patients and their relation with impact, severity and frequency of headaches