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Medication overuse headache (MOH) is a common, disabling and costly disease that it is potentially treatable. Several studies have demonstrated significant reductions in headache frequency after detoxification. From the patients perspective, the effect on disability, anxiety and depression is often equally important. This has been less often examined and mainly in single centre studies.

Disability caused by medication-overuse headache can be considerably reduced by detoxification. Results from multinational COMOESTAS study