English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background  Population studies show that the use of swimming pools is associated with the risk of asthma and allergic diseases among children.    Objective  To explore the associations between blood trihalomethane (THM) concentrations and asthma among U.S. adolescents and assess to what extent the association is modified by active tobacco smoke exposure.    Methods  We included 2359 adolescents aged 12–19 years with measured blood concentrations of chloroform (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), and bromoform (TBM) from the National Health and Nutrition Examination Surveys 2005–2012. Logistic regression models were fitted to assess the odds ratios (ORs) for the association of THM concentrations (three or four categories) with the risk of self-reported   current   and   ever   (lifetime) asthma.    Results  Blood DBCM concentration was associated with a greater risk of   ever   asthma among all adolescents (OR=1.54; 95% confidence intervals: 1.07, 2.21, comparing the extreme exposure categories). The relation was stronger among adolescents exposed to tobacco smoke (OR=3.96; 1.89, 8.30, comparing the extreme exposure categories). We also found positive relationships between brominated THMs (sum of BDCM, DBCM, and TBM) and risk of   ever   asthma and between DBCM and brominated THMs and risk of  current  asthma among adolescents with tobacco smoke exposure. The relative excess risk of   ever   asthma due to the interaction between high blood DBCM and brominated THMs and tobacco smoke exposure was 1.87 (0.30, 3.43) and 0.78 (0.07, 1.49), respectively.    Conclusions  Exposure to THMs is associated with a greater risk of asthma in adolescents, particularly among those exposed to tobacco smoke.

Association of blood trihalomethane concentrations with asthma in US adolescents: nationally representative cross-sectional study