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On behalf of the ASH Research Collaborative (ASH RC) and the Data Hub, I am pleased to provide the hematology community with an update on our progress to date and plans for 2020. The ASH RC is a non-profit organization established by ASH in 2018 to foster collaborative partnerships that accelerate progress in hematology, with the goal of improving the lives of people affected by blood diseases. As a major initiative within ASH RC, the Data Hub aims to create the largest shared information resource within the global hematology community. ASH RC also contains a SCD Clinical Trials Network (SCD CTN), an ambitious project designed to accelerate the development and evaluation of therapies in a large proportion of the United States population affected by SCD. Through the Data Hub, SCD CTN, and projects still to come, the ASH RC will transform research and practice in malignant and nonmalignant hematologic diseases throughout the world, for the benefit of patients and the hematology community.

How FLT3-ITDs and NPM1 Insertions Maneuver Into AML Using the Lymphoid Enzyme TdT to Initiate Replication Slippage