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Three-dimensional sonography enables assessment of uterine morphology. While the pattern of endometrial growth has been well described, little information is available on changes in endometrial and myometrial volume, area, and perimeters. We evaluated the ratio between myometrial and endometrial dimensions and its relation to endometrial thickness of inpatients with normal uterine morphology from our hospital. Routine hormonal assessment on the day of the sonographic exam was extracted from electronic medical records. Correlations between different dimensions of the uterus were examined. A total of 38 3D sonographic data sets were reviewed. A significant correlation was found between estradiol blood levels and endometrial thickness, area, and volume (R = 0.35, 0.53, 0.55, respectively; P &lt; .05). The ratio between the endometrial and myometrial area remained constant regardless of endometrial thickness. The findings of this study suggest that endometrial thickness, area, and volume may correlate with circulating estradiol levels. Endometrial and myometrial changes correlated in more than one dimension.

Endometrial and Myometrial Multidimensional Growth During the Cycle