Open AccessIs it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
Author(s) -
Nurul Yaqeen Mohd Esa,
Rosdina Zamrud,
Nor Salmah Bakar,
Marfu’ah Nik Eezamuddeen,
Mohd Farhan Hamdan
Publication year - 2017
Publication title -
proceedings of singapore healthcare
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
eISSN - 2059-2329
pISSN - 2010-1058
DOI - 10.1177/2010105817716185
Subject(s) - medicine , lung , hepatocellular carcinoma , adenocarcinoma , lung cancer , metastasis , radiology , positron emission tomography , biopsy , pathology , lesion , adenocarcinoma of the lung , cancer
We report the case of a 50-year-old man who was investigated for an incidental finding of a left lung mass following left shoulder pain over a three month period. He also had a significant raised serum alpha-fetoprotein (AFP) level of 29,000, which raised the suspicion of hepatocellular carcinoma with lung metastases. However, there was no detectable liver lesion on multiphase contrasted tomography of the liver and no significant hypermetabolic nodes or distant metastasis seen in the liver on positron emission tomography scan. A lung biopsy confirmed adenocarcinoma with hepatocellular differentiation that would explain the raised serum AFP level.
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