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Seven oxygenated sesquiterpenes 1 to 7 each with a drimane framework were isolated from an organic extract of the nudibranch Ardeadoris rubroannulata collected from Eastern Australia. The structure of pu’ulenal 2 was revised by 1D NOESY, providing a 9Z configuration, while isopu’ulenal 3 has the 9 E configuration previously ascribed to pu’ulenal.

Oxygenated Sesquiterpenes From the Indo-Pacific Nudibranch Ardeadoris rubroannulata: Structure Revision of Pu’ulenal