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Sixteen lanostane-type triterpeneoids were isolated from the fruiting bodies of wild Ganoderma lucidum and G. multipileum. The new structures 3 S,24 S,25,26-tetrahydroxy-5α-lanost-8-en-11-one (1) and ganodermanondiol 24,25-acetonide (10) were elucidated by means of spectroscopic data and Mosher's experiments. Lanosta-7,9(11)-dien-3β-ol (9) strongly inhibited α-glucosidase with the IC 50  values of 198.8 μM in compared with acarbose (IC 50  712.4 μM).

Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies