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Five isoflavanoids including one new, (3 R)–2′,4′,5,7-tetrahydroxy-6-methylisoflavanone (1), were isolated from the aerial parts of Desmodium heterophyllum. Their structures were elucidated using spectroscopic methods. Their inhibitory effects on digestive enzymes α-glucosidase and α-amylase were evaluated. Genistein (5) and dalbergioidin (2) inhibited both enzymes. Their IC 50  values were found at 110.4 and 162.8 μM for α-amylase, and at 257.3 and 412.6 μM for α-glucosidase, respectively.

Isoflavonoids from Desmodium heterophyllum Aerial Parts