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The effect of spongean alkaloids aaptamine (1), isoaaptamine (2), 9-demethylaaptamine (3), aaptanone (4), N-demethylaaptanone (5), and semisynthetic 4- N-methylaaptanone (6) was studied on the growth of seedlings roots of soy { Glycine max (L.) Merr.}, maize ( Zea mays L.), wheat ( Triticum aestivum L.), buckwheat ( Fagopyrum esculentum Moench), and barley ( Hordeum vulgare L.). It was shown that a stimulatory effect depends on the chemical structure of the compounds and species of crop plants. The structural motif of aaptamines 1–3 is essential for a stimulating activity on the growth of seedling roots of soy, maize, and wheat. The oxygenated 1,6-naphthyridine core of aaptanones 5 and 6 is important for their growth stimulating activity on barley roots.

Influence of Aaptamine Alkaloids on the Growth of Seedling Roots of Agricultural Plants