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Five new cardenolide glycosides, amurensiosides L–P (1–5), were isolated from the roots of Adonis amurensis. Their structures were determined based on extensive spectroscopic analysis, including two-dimensional (2D) NMR data, and on the results of hydrolytic cleavage. Compounds 1–5 were evaluated for their cytotoxic activities against HL-60 human promyelocytic leukemia and HSC-2 human oral squamous cell carcinoma cell lines.

Amurensiosides L-P, Five New Cardenolide Glycosides from the Roots of Adonis amurensis