English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this report, the PTP1B inhibitory effect of Calystegia soldanella was investigated. Bioassay-guided fractionation of the crude extracts revealed that the n-hexane fraction had the strongest PTP1B inhibitory effect. Nine known alkyl p-coumarates were isolated from the n-hexane fraction, and each compound was evaluated for its effect on PTP1B. All compounds effectively inhibited PTP1B activity. The IC 50  values of the compounds were 3 (10.8 μg/mL) &gt; 2 (15.5 μg/mL) &gt; 7 (26.6 μg/mL) &gt; 1 (37.0 μg/mL) &gt; 8 (41.2 μg/mL) &gt; 9 (43.4 μg/mL) &gt; 5 (44.7 μg/mL) &gt; 4 (&gt;50 μg/mL) &gt; 6 (&gt;50 μg/mL).

PTP1B Inhibitory Effect of Alkyl p-Coumarates from Calystegia soldanella