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A new lignan glycoside, (-)-(8 S, 8′ R)-thujastandin-4- O-β-D-glucopyranoside (1), together with fourteen known lignanoids (2–15) and one coumarin (16) were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were elucidated by extensive spectroscopic and spectrometric analysis. Compound 16 exhibited cytotoxicity against A549, BGC-823 and Hela cell lines with IC 50  values of 25.9, 20.9 and 18.5 μM, respectively.

A New Lignan Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii