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The chemical constituents from the flower, leaf and stem of Helichrysum armenium DC. (Asteraceae) growing in Iran were obtained by hydrodistillation and analyzed by GC and GC/MS. The oil of flower was characterized by higher amount of limonene (21.2%), α-cadinol (18.2%), borneol (11.9%), δ-cadinene (9.0%), bornyl acetate (8.0%) and α-humulene (7.3%). Twenty one constituents representing 96.2% of the chromatographical leaf oil were identified of which limonene (29.2%), α- pinene (14.4%), caryophyllene oxide (6.5%), α-gurjunene (6.3%), bornyl acetate (5.5%) and torreyol (5.2%) were the major components. The main components of the stem oil were limonene (23.6%), α-pinene (13.4%), spathulenol (6.4%), α-gurjunene (6.3%), caryophyllene oxide (5.3%), bornyl acetate (5.2%), β-cubebene (4.8%) and δ-cadinene (4.3%). The composition of the oils is different, although the most abundant components are identical in leaf oil (96.2%). The antimicrobial effect of flower, leaf and stem essential oils from Helichrysum armenium was studied according to the agar diffusion cup method. The essential oils had a moderate effect on the Gram-positive and Gram-negative bacteria and had a substantial fungicidal effect on the fungi under study.

Constituents and Antimicrobial Activity of the Essential Oils from Flower, Leaf and Stem of Helichrysum armenium