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Riboflavin can be photosensitized to produce reactive oxygen species. In the present study, a DNA damage assay was developed based on the photo reaction of riboflavin. In this test system, oxyresveratrol showed higher DNA protective effect than the well-known antioxidants Trolox and ascorbic acid. The results suggest potential applications for oxyresveratrol as an antiaging agent and a riboflavin stabilizer.

Oxyresveratrol Protects against DNA Damage Induced by Photosensitized Riboflavin