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Chemical analysis of the stem bark of Erythrina sigmoidea Hua yielded two new flavonoids, designated sigmoidin M (1) and sigmoidin N (2). Their structures were established by chemical and spectroscopic means as 5,7-dihydroxy-3′-O-prenyl-(3″,4″-dihydroxy-2″,2″-dimethylpyrano)[5″,6″:4′,5']flavanone (1) and 5,7,3′-trihydroxy-(3″-hydroxy-2″-(1-hydroxyisopropyl)-[4′,5:4″,5″]furanoflavanone (2), respectively. Sigmoidin M exhibited antimicrobial activity.

Flavanones from the Stem Bark of Erythrina Sigmoidea