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Two piperonyl derivatives, seven coumarins and two furoquinoline alkaloids were isolated from the aerial parts of a new species of Brombya [Brombya sp. nov. (Gap Creek) (Rutaceae)]. Three of the compounds were new natural metabolites; 7-(3,4-methylenedioxyphenyl)octene-2-one (7,8-dehydromoskachen D), the coumarin 6-(1ξ,2ξ,3-trihydroxy-3-methylbutyl)-7-hydroxy-2H-1-benzopyran-2-one, and the furoquinoline alkaloid 4,5,6,7-tetramethoxyfuro[2,3-b]quinoline (5,6,7-trimethoxydictamnine). The secondary metabolites isolated in this study are typical of the Rutaceae, contrasting with earlier studies on the only other species of Brombya, B. platynema, which yielded only brombyins, for which 7,8-dehydromoskachen D is a possible precursor.

Novel Metabolites from the Stem Bark of Brombya sp. Nova (Gap Creek) (Rutaceae)