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Purpose   To evaluate the impact of pressure-regulated volume control (PRVC/VC+) use on delivered tidal volumes in patients with acute respiratory distress syndrome (ARDS) or at risk for ARDS.Materials and methods   Retrospective study of mechanically ventilated adult patients with severe sepsis or septic shock.Results   A total of 272 patients were divided into patients with recognized ARDS, patients without ARDS, and patients with unrecognized ARDS. Over 90% of patients were ventilated with PRVC on admission, resulting in delivered tidal volumes significantly higher than set tidal volumes among all groups at all time points, even after ARDS recognition ( p &lt; 0.001). Tidal volumes were lower for patients with pulmonary sepsis as compared to those with a nonpulmonary origin ( p &lt; 0.001).Conclusions   Using PRVC promotes augmented delivered tidal volumes, often in excess of 6 mL/kg ideal body weight. Correct recognition of ARDS and having pulmonary sepsis improves compliance with low-stretch protocol ventilation.

the journal of the intensive care society/journal of the intensive care society

Use of pressure-regulated volume control in the first 48 hours of hospitalization of mechanically ventilated patients with sepsis or septic shock, with or without ARDS