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Several sonographically guided injection methods have been described to treat carpal tunnel syndrome. In most cases, the medication diffuses through the carpal tunnel to the site of maximum compression of the nerve after being injected proximally. In this article, we describe a novel method of sonographically guided carpal tunnel injection that utilizes a distal-to-proximal, in-plane, and transligamentous approach. This novel method may provide ergonomic as well as safety advantages to both clinicians and patients, and should be considered by those performing carpal tunnel injections.

A Sonographically Guided In-Plane Distal-to-Proximal Transligamentous Approach to Carpal Tunnel Injections