Does Corticospinal Tract Connectivity Influence the Response to Intensive Bimanual Therapy in Children With Unilateral Cerebral Palsy? | Zendy

Ana R.P. Smorenburg | Zendy; Andrew M. Gordon | Zendy; HsingChing Kuo | Zendy; Claudio L. Ferre | Zendy; Marina B. Brandão | Zendy; Yannick Bleyenheuft | Zendy; Jason B. Carmel | Zendy; Kathleen M. Friel | Zendy

Open Access

Does Corticospinal Tract Connectivity Influence the Response to Intensive Bimanual Therapy in Children With Unilateral Cerebral Palsy?

Author(s) -

Ana R.P. Smorenburg,

Andrew M. Gordon,

HsingChing Kuo,

Claudio L. Ferre,

Marina B. Brandão,

Yannick Bleyenheuft,

Jason B. Carmel,

Kathleen M. Friel

Publication year - 2016

Publication title -

neurorehabilitation and neural repair

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.651

H-Index - 106

eISSN - 1552-6844

pISSN - 1545-9683

DOI - 10.1177/1545968316675427

Subject(s) - cerebral palsy , corticospinal tract , physical medicine and rehabilitation , pyramidal tracts , psychology , functional connectivity , rehabilitation , medicine , neuroscience , magnetic resonance imaging , diffusion mri , radiology

Reorganization of the corticospinal tract (CST) can occur in unilateral spastic cerebral palsy (USCP). The affected hand can be controlled via (1) typical contralateral projections from the lesioned hemisphere, (2) ipsilateral projections from the nonlesioned hemisphere, and (3) a combination of contralateral and ipsilateral projections (ie, bilateral). Intensive bimanual therapy and constraint-induced movement therapy (CIMT) improve hand function of children with USCP. Earlier it was suggested that the CST connectivity pattern may influence the efficacy of CIMT.

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