Open AccessTraining Intensity Affects Motor Rehabilitation Efficacy Following Unilateral Ischemic Insult of the Sensorimotor Cortex in C57BL/6 Mice
Author(s) -
Jared A. Bell,
Malerie L. Wolke,
Ryan C. Ortez,
Theresa A. Jones,
Abigail L. Kerr
Publication year - 2014
Publication title -
neurorehabilitation and neural repair
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.651
H-Index - 106
eISSN - 1552-6844
pISSN - 1545-9683
DOI - 10.1177/1545968314553031
Subject(s) - rehabilitation , physical medicine and rehabilitation , intensity (physics) , stroke (engine) , psychology , training (meteorology) , motor learning , medicine , motor cortex , motor skill , physical therapy , neuroscience , meteorology , mechanical engineering , physics , engineering , stimulation , quantum mechanics
Motor rehabilitative training improves behavioral functionality and promotes beneficial neural reorganization following stroke but is often insufficient to normalize function. Rodent studies have relied on skilled reaching tasks to model motor rehabilitation and explore factors contributing to its efficacy. It has been found that greater training intensity (sessions/day) and duration (training days) facilitates motor skill learning in intact animals. Whether rehabilitative training efficacy varies with intensity following stroke is unclear.
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