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Many programs and functions in statistical packages focus on the final stage of clinical trials, that is, the data analysis. In this article, I aim to assist in the early stages of clinical trials, specifically, the design of phase II single-arm trials. I present the new command stopbound, which calculates stopping boundaries and operating characteristics based on monitoring an adverse event, efficacy, or an adverse event and efficacy.

Stata Command for Calculating Adverse Event and Efficacy Stopping Boundaries for Phase II Single-Arm Trials