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Background:   Inpatient multidisciplinary rehabilitation (MDR) can improve health-related quality of life (HRQoL) in multiple sclerosis (MS) patients. However, the evidence of a long-term benefit is limited.Objectives:   To investigate the long-term effectiveness of inpatient MDR on HRQoL in MS patients.Methods:   We conducted a randomized controlled partial crossover trial with 427 MS patients.Results:   Statistical significant long-term improvements in HRQoL were found in three of the six outcome measures at 12-month follow-up. Three in four suggested minimal clinically important differences (MCIDs) were unmet.Conclusion:   These results indicate that the administration of inpatient MDR may lead to long-lasting improvements in HRQoL in MS patients.

multiple sclerosis

Can inpatient multidisciplinary rehabilitation improve health-related quality of life in MS patients on the long term – The Danish MS Hospitals Rehabilitation Study