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The number and size of open-access developmental data sets that include brain and behavioral information have dramatically increased in recent years (Fig. 1; see also Table S1 in the Supplemental Material). These collaborative initiatives represent a new era of science that democratizes data access, facilitates scientific discovery, boosts statistical power, enhances reproducibility and replication, and can inform policy (Rosenberg et al., 2018). However, to use these data responsibly, we must consider the broader social context, the dynamic and interactive process of development, and the strength and limitations of the data when formulating our research questions, designing statistical models, and interpreting our findings. Here, we use the Adolescent Brain Cognitive Development (ABCD) Study, the largest longitudinal study of brain development and youth health in the United States to date, to suggest best practices for responsible data use. To be developmentally informed and responsible users of these data, we must consider (a) the heterogeneity of experiences within the broader social context in which development occurs and (b) the potential for adaptation to the environment and developmental change. Consider the Broader Social Context in Which Development Occurs

Responsible Use of Open-Access Developmental Data: The Adolescent Brain Cognitive Development (ABCD) Study