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An analysis of 541 patients having total body perfusion under hypothermia (30°–33°C) showed that the use of pulsatile as against constant flow perfusion was not associated with a reduction in bicarbonate requirement, though the use of a vasodilator was. The implications of this are discussed.

Bicarbonate Requirements during Hypothermic Cardiopulmonary Bypass the Relative Effects of Pulsatile Flow