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Using 10 different infusion bag pressure pumps, indicated manometer pressures were compared with measured infusion pressures proximal to the flow-regulating device in an in vitro experiment. Flow rates delivered through the flow-regulating device were gravimetrically measured at different monitored pressure levels.    Significant differences were found between manometer and measured infusion pressures among the tested pressure bag pumps (e.g. 500 ml bag volume pressurized to 300mmHg manometer pressure: 219.6±7.8 to 407.2±2.7 mmHg). The infusion pressures were additionally affected by the vertical level of the infusion bag pump and by the volume of the infusion bag. Flow rates delivered through the flow-regulating device were directly correlated to the measured infusion pressure (r  2  =0.9926).    Differences in flow rates can have a considerable impact on maintaining catheter patency and avoidance of fluid overload and retrograde flushing into the central arterial circulation in neonates and small children.    A simple manoeuvre using the invasive pressure transducer allows monitoring and adjustment of the infusion pressure in the clinical setting.

Variability in Infusion Pressure and Continuous Flow Rate Delivered from Pressurized Bag Pump Flush Systems