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Objective   To investigate the associations between serum vitamin D, calcium and uterine fibroids in a Chinese female population.Methods   In this case-control study, adult female patients with fibroids (cases) were compared with females without fibroids (controls) in terms of serum 25-hydroxyvitamin D (25OHD) and calcium levels.Results   Out of 546 total participants (mean age, 41.68 ± 5.99 years; 279 with fibroids and 267 without fibroids), only 232 had serum 25OHD levels above the sufficient threshold (&gt;20 ng/ml). In addition, females with fibroids had lower serum 25OHD levels versus those without fibroids. The prevalence of fibroids in females with deficient ( 20 ng/ml) 25OHD levels. Serum calcium levels were within normal range in both groups.Conclusion   Hypovitaminosis D was highly prevalent among a population of Chinese females of reproductive-age, and serum 25OHD levels were lower in female patients with fibroids.

The associations between serum vitamin D, calcium and uterine fibroids in Chinese women: a case-controlled study