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A method is described for the simultaneous determination of urinary HMMA, 5-HIAA and HVA by HPLC with electrochemical detection. The method was evaluated over an 8-month period and has thus far identified 2 cases of phaeochromocytoma, 1 case of neuroblastoma and 2 of carcinoid tumour.

annals of clinical biochemistry

Simultaneous Assay for Urinary 4-Hydroxy-3-Methoxymandelic Acid, 5-Hydroxyindoleacetic Acid and Homovanillic Acid by Isocratic HPLC with Electrochemical Detection