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A method of selective concentration of the minor urinary purines is described based on selective ‘adsorption on to ion-exchange resins. Methods of semi-quantitative determination of the amount of each purine present are described based on two dimensional paper chromatography followed by direct inspection under short wave ultra-violet light, by preparation of contact prints and by elution of the purine spots followed by measurement of the optical density.

Semiquantitative Analysis of Urinary Purines Designed to Search for Metabolic Disorders