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Approximately 37 million acute care injury visits are made in the United States each year, and 2.5 million individuals are so severely injured that they require inpatient hospitalization. Few investigations have used pharmacoepidemiologic methods to determine which medications with strong theoretical support for secondary prevention of posttraumatic stress disorder (PTSD) are already in widespread use in acute care settings.

From Bedside to Bench: How the Epidemiology of Clinical Practice Can Inform the Secondary Prevention of PTSD