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Prostaglandins were first discovered by von Euler in the late 1940s to be active principles in semen that induced uterine contractility. Since then, interest in the field has waxed and waned. Indeed, through much of the 50s and 60s, prostaglandin research remained the arcane preserve of the dedicated few. It maintained a continuing emphasis on reproductive biology but was eclipsed in the popular vision by those other stepchildren of von Euler’s creativity, the catecholamines.

Series Introduction: COX in a crystal ball: current status and future promise of prostaglandin research