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The four major NIH-supported career development K awards are the K01, K08, K23, and K99, which comprise 70% of the investment allocated to the 15 K-type career awards. One measure of early career success is the conversion of the K award to an NIH R01 grant. Analysis of the outcomes of K-to-R01 conversion within 5 years of receipt of the K award across the NIH during the period 2008–2012 showed that K99 awards have a uniform (up to 60%) increased conversion success compared with the K01, K08, and K23 mechanisms. The K99 success continued to 7 years for the available analysis period (2008–2010). The largest number of K award recipients and their conversion to R01 were at institutions located in California, Massachusetts, and New York. Several measures that may enhance conversion of the K01/K08/K23 and diversify the distribution of the awardees are highlighted. Investing in early-career researchers The NIH has made significant investments in researcher career development, including a range of research training (T-type), career development (K-type), and fellowship (F-type awards) (1). In federal fiscal year 2017 alone, NIH directed 4.5% ($1.5 billion) of its $33.1 billion budget to K ($680 million), T ($664 million), and F ($158 million) grants (2, 3). After completion of higher degree training (e.g., PhD/MD/DDS/PharmD), four NIH-supported awards account for nearly 70% of 15 K-type [...] Viewpoint

NIH Career Development Awards: conversion to research grants and regional distribution