English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The post-transfusion survival of stored human or rabbit erythrocytes can be influenced favorably by the addition of certain purine nucleosides to the preserving solution (1-5). It had been noted earlier that the water-soluble organic phosphates of the erythrocyte disappeared to a large extent during storage (6), but nucleosides have been found to retard this change and, if added late in storage followed by a short incubation at 370 C, they bring about appreciable resynthesis of the organic phosphate (7-10). Early studies on the nature and changes of the phosphate compounds of the erythrocyte during storage were performed for the most part by using hydrolysis rates and paper chromatography (1, 2, 7-9). Recently improved technics for the isolation and identification of the metabolic intermediates, which use columns of ion exchange resin and more specific chemical and enzyme analytical methods, have greatly extended our knowledge of the normal carbohydrate intermediates of the human erythrocyte and make possible a more detailed analysis of changes occurring during storage (11-18). We have previously reported on the phosphorylated carbohydrate intermediates of the rabbit erythrocyte during storage with and without inosine ( 19). The present paper describes a similar study in which the glycolytic intermediates and nucleotides of human erythrocytes were analyzed at biweekly intervals during 8 weeks of storage at 40 C in acid citrate dextrose (ACD) and in ACDplus inosine (ACDI).

the journal of clinical investigation/the journal of clinical investigation

PHOSPHORYLATED CARBOHYDRATE INTERMEDIATES OF THE HUMAN ERYTHROCYTE DURING STORAGE IN ACID CITRATE DEXTROSE. I. EFFECT OF THE ADDITION OF INOSINE AT THE BEGINNING OF STORAGE*