English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Plasma free fatty acids (also variously referred to as nonesterified fatty acids and unesterified fatty acids) have assumed importance as a small but very rapidly metabolized component of serum lipids (1, 2). Their derivation from the fat of adipose tissue has been demonstrated and may represent an important form in which stored fat is mobilized, transported and made available for fuel during starvation (3). The concentration of free fatty acids (FFA) in plasma increases during starvation (4), in the "metabolic" starvation of diabetic acidosis (5) and of hyperthyroidism (6). When an overnight fast is terminated by the administration of 50 to 100 g of carbohydrate, an abrupt fall in concentration of plasma FFA occurs within one-half hour and lasts for several hours, and a similar but less marked drop follows a protein meal (1, 2). On the other hand, following a fat meal of equal or greater caloric value, the FFA either do not change appreciably or rise much as they do during a similar period of fasting (2, 7). The decrease in concentration of FFA appears to occur in response to an-increase in carbohydrate utilization. The absence of such a drop in concentration after a fat meal would seem to indicate insensitivity of the FFA regulatory system to fat or merely the substitution of FFA derived from ingested fat for those derived from adi-pose fat (3). An alternative possibility is herein suggested, namely that relative inefficiency of fat metabolism in persons adapted to a high carbohydrate diet might account for the failure of a fat meal to cut off the FFA-mobilizing mechanism. Any nutritional or metabolic maneuvers aimed at increasing fat combustion might alter the response of plasma FFA to a fat meal. The present study is concerned with the change in plasma lipids including FFA when a fat meal was administered at the end of a period of starvation lasting for several days. The subjects, who were in their twenties and were free of known disease, were 6 males, and 2 females. A third woman became ill from the effects of the first 24 hours of starvation and had to be dropped from the study. To 6 of the subjects a fat breakfast was given after an overnight fast, and again at the end of a period of starvation lasting from 2 to 7 days. During the starvation nothing but water was ingested. The subjects carried on their …

EFFECT OF PREVIOUS STARVATION ON THE RESPONSE OF PLASMA LIPIDS AND FREE FATTY ACIDS TO A FAT MEAL*