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The existence, in inbred strains of mice, of two different types of electrophoretic hemoglobin patterns has been demonstrated with the method of paper electrophoresis (1). Preliminary studies of the distribution of these different patterns in the inbred strains tested indicated strongly a genetic basis of hemoglobin differences in mice. It is the purpose of the present communication to report the results of breeding experiments designed to test the assumption of a hereditary transmission of these differences and to determine the mode of inheritance.

THE HEREDITARY TRANSMISSION OF HEMOGLOBIN DIFFERENCES IN MICE 1