English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The existence of a specific abnormality of lipid metabolism in patients with atherosclerosis has been suggested by recent studies which have shown that the concentration of certain serum lipoproteins in patients with coronary disease is statistically different from that found in "normal" individuals. Gofman and his co-workers (1) found in such patients an elevation of a beta lipoprotein sub-fraction defined by ultracentrifugal flotation rates between Sf 10 and 20. Russ, Eder, and Barr (2, 3) measured the cholesterol content of precipitated serum lipoprotein fractions and found that the total beta lipoprotein fraction was increased in serum from a group of atherosclerotic patients as compared to a control group made up largely of hospital personnel. Similar results have been obtained by Nikkila (4), who measured the cholesterol content of electrophoretically separated protein fractions, and by Antonini et al. (5) and Kroetz and Fischer (6) who measured lipoprotein concentration in terms of the lipid dye binding of serum proteins separated by paper electrophoresis. Studies on the validity and reproducibility of two relatively simple methods for the estimation of electrophoretically separated serum lipoproteins by measurement of their cholesterol content and dye binding capacity have recently been reported from this laboratory (7, 8). These methods are not subject to significant error due to loss of lipoprotein bound dye during alcohol rinsing, oxidation of cholesterol, or tailing of lipoprotein during electrophoresis similar to that found with albumin. The studies reported here were carried out in order to test the large scale application of these methods, to compare the results of the two methods with each other and with ultracentrifugal methods, and to confirm further the association of

A STUDY OF SERUM LIPOPROTEINS IN NORMAL AND ATHEROSCLEROTIC PATIENTS BY PAPER ELECTROPHORETIC TECHNIQUES