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The electrophoretic patterns of plasma obtained from patients with rheumatoid arthritis have been described by many investigators and are discussed in the preceding paper (1). The electrophoretic distribution of proteins in synovial fluid has been studied less extensively (2-5). It seemed of interest, therefore, to determine the various patterns which may occur in joint fluid of patients with rheumatoid arthritis and to determine whether a correlation exists with the duration and severity of the disease and with other characteristics of joint fluid which have been shown to reflect the degree of inflammation of the synovial tissue (6).

The Electrophoretic Patterns of Proteins in Synovial Fluid and Serum in Rheumatoid Arthritis12