English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Current opinion concerning the impaired output of water in patients suffering from cirrhosis of the liver (1, 2) or from congestive heart failure (3) emphasizes primarily the impaired excretion of sodium with consequent retention of water, and only secondarily tends to implicate the neurohypophysial antidiuretic hormone as a responsible agent (4, 5). The present studies and discussion are meant to explore more fully the physiology of this hormone in these diseases. The relationship of the antidiuretic hormone to the abnormal retention of water in edematous states has been studied in several ways. Thus, following oral hydration with water, impaired water diuresis 5 has been demonstrated in patients with cirrhosis of the liver (4, 6, 7), and a water tolerance test based on this phenomenon has been employed for some years. A subnormal urinary excretion of water following intravenous hydration with 5 per cent glucose in water in some patients with cirrhosis has also been reported (4). Similarly, delayed water diuresis following the

STUDIES IN EDEMA. IV. WATER RETENTION AND THE ANTI-DIURETIC HORMONE IN HEPATIC AND CARDIAC DISEASE 12