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In 1948, Hargraves, Richmond, and Morton (1) described a new cellular element in the bone marrow of patients with acute systemic lupus erythematosus. This element, referred to as the "L.E. cell," has been confirmed by a number of investigators, and has been suggested as a diagnostic aid (2). The L.E. cell may be formed during the incubation of normal homologous or heterologous leucocytes (3) with the sera of some patients suffering

STUDIES ON DESOXYRIBONUCLEASE IN SYSTEMIC LUPUS ERYTHEMATOSUS. NON-PARTICIPATION OF SERUM DESOXYRIBONUCLEASE IN THE “L.E. PHENOMENON” 1