English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The mechanisms by which the body compensates for a decrease in blood volume have not been thoroughly studied in man. All physicians are aware that from 500 to 1000 ml. of blood can be removed from a person of average size without producing any symptoms, if the body is horizontal. If the blood is removed rapidly, hemodilution plays little part in the immediate adjustment. Do the arterioles constrict, maintaining the arterial pressure at a normal level at the expense of blood flow to the tissues? Is the atrial pressure maintained at the normal level by venous constriction? Or is it possible that up to a certain point, the heart can function effectively with a falling atrial pressure so that the circulation can be maintained without either arteriolar or venous constriction in spite of a moderate decrease in blood volume? The purpose of this paper is to describe the changes in the circulation in normal subjects caused by moderate loss of blood from the body, either as the result of venesection or by pooling blood in the extremities through the application of venous tourniquets. During the experiments, acute circulatory collapse (primary shock) occurred in three instances and quantitative observations were made on the changes occurring in the circulation.

the journal of clinical investigation/the journal of clinical investigation

THE EFFECT OF VENESECTION AND THE POOLING OF BLOOD IN THE EXTREMITIES ON THE ATRIAL PRESSURE AND CARDIAC OUTPUT IN NORMAL SUBJECTS WITH OBSERVATIONS ON ACUTE CIRCULATORY COLLAPSE IN THREE INSTANCES 1