English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Recent studies (1 to 9) have reported the occurrence of vitamin A deficiency in patients having cirrhosis of the liver. It has also been shown that a lowering of the amount of vitamin A available to the tissues may result from reduced vitamin A intake (10 to 14), and from faulty gastro-intestinal absorption (6, 15, 16), especially when associated with jaundice (16). It is known, moreover, that febrile states reduce the level of vitamin A in the blood (17, 18). Since both faulty gastro-intestinal absorption and fever (19) may occur in Laennec's cirrhosis, it is essential in a study of vitamin A deficiency in relation to this disease that these factors be controlled. In many of the published studies of the subject, either the appropriate controls are lacking, or the conditions bearing on these factors are unspecified. In previous papers data were presented which revealed that (a) patients with cirrhosis of the liver may have greatly delayed dark adaptation which is improved by massive daily doses of vitamin A (3, 4); (b) there is no evidence in such patients of a causal relation between the level of vitamin A in the blood and the dark adaptation time (20); (c) the vitamin A concentration in the liver of rats with carbon tetrachloride cirrhosis was half that of normal rats fed the same amount of food and of vitamin A (21). It is our present purpose to compare the dark adaptation time and the blood plasma concentration of vitamin A. and of total carotenoid found in patients with Laennec's cirrhosis with those found in normal persons and in patients with certain other diseases.

VITAMIN A DEFICIENCY IN LAENNEC'S CIRRHOSIS. THE RELATIVE SIGNIFICANCE OF THE PLASMA VITAMIN A AND CAROTENOID LEVELS AND THE DARK ADAPTATION TIME 1