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In a previous paper (1) a method for studying the rotatory values present in human blood plasma has been discussed, and a series of comparative reducing and rotatory values have been presented, recording the values obtained from normal individuals and hospital patients, exclusive of diabetics and nephritics. It was found in this series that the rotatory values of plasma ultrafiltrates, if expressed in terms of glucose generally proved to be lower than the reducing values and in fact, good agreement between the two was recorded in only a few instances. These recognized differences between the reducing and rotatory values were designated in the experiments as. R-P values (the reducing minus the polariscopic value) and, in the previous senes, were found to range between the equivalent of 0 and 0.130 gram of glucose per 100 cc., averaging about 0.040 gram per 100 cc. The rotatory values proved to be somewhat irregular, however, for in studying the ultrafiltrates over a period of seventytwo hours, fluctuations were noted, amounting to an average value of i0.022 gram of glucose, whereas the reducing values remained practically unchanged. These findings conform in general to those which have been reported by other investigators whose work has been reviewed in the previous communication. At the outset, however, it is well to re-emphasize the fact that studies of the R-P values of blood plasma consist essentially in the measurement of a rather complex property of human blood plasma and not

A COMPARATIVE STUDY OF THE ROTATORY AND REDUCING PROPERTIES OF PLASMA ULTRAFILTRATES FROM DIABETIC AND NEPHRITIC PATIENTS