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The relation of the form of the electrocardiogram to the site of stimulation in the ventricles still remains an open question, although patients have been studied from this point of view and many experiments on animals have been performed. Einthoven (1) in 1908 was the first to attempt to localize the site of origin of ventricular premature contractions by an analysis of patients' electrocardiograms. Even at the present time such localization cannot be made with any degree of accuracy in the human heart.

DEPENDENCE OF THE FORM OF THE ELECTRO-CARDIOGRAM UPON THE SITE OF MECHANICAL STIMULATION OF THE HUMAN VENTRICLES