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Epidemiology is the study of the distribution and patterns of health characteristics and their causes in well-defined populations. Over the last few decades, well-designed traditional epidemiologic studies have defined the prevalence of and elucidated risk factors for eye diseases such as cataract, refractive error, open-angle glaucoma, age-related macular degeneration, and diabetic retinopathy. These discoveries into the etiology of eye diseases have facilitated the understanding of pathogenic mechanisms, the modification of risk factors to prevent disease, and the identification of high-risk individuals for therapeutic interventions.

Translational Epidemiology in Ophthalmology: From Etiologic Research to Personalized Health Impact