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Mice lacking ATP-binding cassette transporter 4 (ABCA4) and retinol dehydrogenase 8 (RDH8) mimic features of human Stargardt disease and age-related macular degeneration. RNA-sequencing of whole eyes was done to study early gene expression changes in Abca4-/-Rdh8-/- mice.

Acute Stress Responses Are Early Molecular Events of Retinal Degeneration inAbca4−/−Rdh8−/−Mice After Light Exposure

Acute Stress Responses Are Early Molecular Events of Retinal Degeneration inAbca4^−/−Rdh8^−/−Mice After Light Exposure