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Treatment with corticosteroids can result in ocular hypertension and may lead to the development of steroid-induced glaucoma. The extent to which biomechanical changes in trabecular meshwork (TM) cells and extracellular matrix (ECM) contribute toward this dysfunction is poorly understood.

Dexamethasone Stiffens Trabecular Meshwork, Trabecular Meshwork Cells, and Matrix