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Optic nerve injury has been found to be dramatically reduced in a genetic mouse glaucoma model following exposure to sublethal, head-only irradiation. In this study, the same radiation treatment was used prior to experimental induction of elevated intraocular pressure (IOP) to determine if radiation is neuroprotective in another glaucoma model.

Radiation Pretreatment Does Not Protect the Rat Optic Nerve From Elevated Intraocular Pressure-Induced Injury